Authors: Labrie F, Luu-The V, Bélanger A, Lin S-X, Simard J, Pelletier G.
Publication Year: 2005
Citation: J Endocrinol 2005; 187:169-96.
These researchers suggest the use of DHEA for physiological hormone replacement because of its nature as a hormone precursor, producing estrogens and testosterone in the hormone-dependent target tissues precisely according to local needs. It could thus alleviate many of the symptoms of hormone deficiency while avoiding the systemic side effects of too much direct hormone therapy with estrogens or testosterone. They call this new concept “intracrinology” as opposed to endocrinology and suggest that it offers new options for menopausal women.