Oral micronized progesterone. Bioavailability pharmacokinetics, pharmacological and therapeutic implications–a review.

Authors: Sitruk-Ware R, Bricaire C, De Lignieres B, Yaneva H, Mauvais-Jarvis P.

Publication Year: 1987

Citation: Contraception 1987; 36(4): 373-402.

This paper reviews the effects and benefits of oral micronized progesterone. Progesterone exhibits anti-estrogenic effects, anti-androgenic effects, and anti-mineralocorticoid effects in addition to its progestational effects. No side effects have been reported for micronized progesterone with respect to lipid profile, coagulation, or blood pressure, leading the authors to recommend micronized progesterone as suitable for treatment of PMS, menopause, irregular cycles, and pregnancy maintenance.

http://www.ncbi.nlm.nih.gov/pubmed/3327648