The role of testosterone in the management of hypoactive sexual desire disorder in postmenopausal women.

Authors: Krapf JM, Simon JA.

Publication Year: 2009

Citation: Maturitas. 2009; 63(3):213-9.

This article reviews testosterone’s role in sexual function in women.  Research is going on to study the safety and effectiveness of transdermal testosterone therapy in women with low sexual desire, sometimes called HSDD (hypoactive sexual desire disorder) if it leads to distress.  The prevalence of this disorder is highest in women who are surgically menopausal, i.e., they have had both ovaries removed, which results in a sudden decline in testosterone levels that leads to a reduced desire for sex and less satisfying sex.  The authors review clinical studies of transdermal testosterone therapy, both with and without estrogen, concluding that it is safe and effective in women struggling with HSDD.