Dehydroepiandrosterone replacement in women with adrenal insufficiency.

Authors: Arlt W, Callies F, Van Vlijmen JC, Koehler I, Reincke M, Publication Year: 1999 Citation:  N Eng J Med 1999;341(14):1013-20. This double-blind crossover study reviewed alternately the effects of 50mg of oral dehydroepiandrosterone (DHEA) daily with placebo in 24 women with adrenal insufficiency. Participants were evaluated using established well-being (depression and anxiety scores) and sexuality …