Orally and transdermally replaced estradiol improves endothelial function equally in middle-aged women after surgical menopause.

Authors: Zegura B, Keber I, Sebestjen M, Borko E. Publication Year: 2003 Citation: Am J Obstet Gynecol 2003;188(5):1291-6. Forty-three surgically induced (6 weeks postop) menopausal women were randomly assigned in a double-blind study to 28 weeks of 2.0mg oral or 50mg transdermal estradiol. Looking at blood flow through the brachial artery, flow-mediated dilation (ultrasound) in …

Effects of progesterone on the inflammatory response to brain injury in the rat.

Authors: Grossman KJ, Goss CW, Stein DG. Publication Year: 2004 Citation:┬áBrain Res. 2004;1008(1):29-39. Progesterone has a known anti-inflammatory effect. In this study, male rats treated with progesterone (4 mg/kg) and/or vehicle, were examined with respect to cellular inflammatory response to frontal cortex injury on postsurgical days 1, 3, 5, 7 and 9. The treated mice …